Colospa 135 mg tablets
Colospa 135 mg tablets is a musculotropic antispasmodic medication used in the treatment of irritable bowel syndrome. It is also indicated for treatment of gastrointestinal spasm caused by a primal organic disorder.
Mechanism of its action consists in relaxing of gut muscles at the cellular level. Colospa 135 mg tablets blocks transfer of Na+ through fast channels of myocyte into th cell and also inhibits calcium-depot replenishment, thus it performs a dual effect on bowels causing them to relax. It does not affect muscles of bronchi or uterus. No significant inhibition of normal peristalsis has been observed. This drug is used to treat a spasm of gastrointestinal organs (including due to organic disease), intestinal colic, biliary colic, irritable bowel syndrome (symptomatic treatment of pain and cramps, and intestinal disorders and discomfort) in adults.